Antibiotic resistance pattern of aerobic bacterial isolates from patients with skin and soft tissue infections in Karaikal

Skin and Soft Tissue Infections (SSTIs) are considered as non-fatal burden with significant morbidity disability. The important challenge of severe SSTIs is choosing a drug for empirical treatment. From this region, only limited local antibiogram data available. To determine the frequency different aerobic bacteria isolated from patients attending dermatology surgery departments GH, Karaikal to study antibiotic resistance pattern isolates. This prospective, cross-sectional 100 samples. Standard protocol was followed collection, processing, identification susceptibility testing. All isolates were screened methicillin subsequently subjected Oxacillin E-strip Vancomycin know minimum inhibitory concentration (MIC) value. Isolates Gram negative bacilli resistant one or more carbapenems tested carbapenemase production using Modified Carbapenem Inactivation Method (MCIM) multi (MDR) organisms identified. Most effective sensitive (MSSA) Clindamycin (82.75%), Gentamicin (80.95%) Cotrimoxazole (75%). (MRSA) incidence 6.89% (2/29). Around 66.67% (4/6) Cefoxitin resistant. carbapenem found be 13.88% (5/36). 43.13% (22/51) MDR. presence MRSA producing worrisome. Further, routine surveillance needed monitor trends in pattern. However, paves way judicious use antibiotics treatment prevent development future.